What Sixera Pharma Does

Sixera Pharma is a biopharmaceutical company based at the Karolinska Institute Science Park in Stockholm. The company was founded to develop basic research findings into treatments for skin diseases.

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About Netherton syndrom

What is Netherton syndrom?

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Netherton disease is a rare disorder affecting the skin, hair and immune system. Symptoms are present at birth and include red, scaly skin. Other symptoms include outbreaks of red, circular scaly rashes, thin, fragile hair (bamboo hair), and immune reactions such as hay fever, asthma, itchy skin, and eczema. Dehydration and infection are common and can be serious. 

Babies tend to grow slowly and have poor weight gain. Netherton syndrome is caused by the SPINK5 gene not working correctly. It is inherited in an autosomal recessive pattern. Netherton syndrome is diagnosed based on clinical examination, the symptoms, and genetic testing.

The symptons starts early

Some examples of Netherton syndrom symptoms

Want to learn more about the symptons?

01.
Abnormal hair morphology

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02.
Acanthosis nigricans

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03.
Asthma

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04.
Congenital nonbullous ichthyosiform erythroderma

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05.
Eczema

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06.
Fine hair

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Sixera Pharma and Netherton syndrom

Improving lives with our discovery

The founders of Sixera Pharma discovered key genes and the mechanisms regulating skin formation and barrier functions critical for the Netherton syndrome. The discovery resulted in the development of a new treatment of the disease, which is of great importance as no targeted treatment is available for the disease today. The new treatment is expected to drastically improve the quality of life for Netherton patients, which is an extremely vulnerable group of patients.

The clinical development of the treatment is carried out through a network of academic and industrial collaborations backed up by comprehensive pre-clinical work, along with development of regulatory documentation

The team has a combined experience of 30+ years

We develop drugs that restore the balance in diseased skin.

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We are always looking for new ways to connect

If you are in a position to help our project or know someone that should be on our team  you can contact us here.

News from the team

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